Albendazole
Uses of Albendazole
The primary use of Albendazole is in managing various parasitic worm infections, including neurocysticercosis, cystic hydatid disease, and infections caused by roundworms, hookworms, pinworms, whipworms, and other helminths. It falls under the broad-spectrum antiparasitic medications category.
Apart from these primary indications, it is also used in managing other helminthic infections caused by different types of worms.
Side effects of Albendazole
Abdominal pain
Nausea
Vomiting
Diarrhoea
Headache
Dizziness
How Albendazole works
Albendazole is used for treating a variety of parasitic worm infections.
Albendazole belongs to the category of broad-spectrum antiparasitic medicines.
The medicine binds selectively to a specific site called the beta-tubulin in parasitic worms, thus preventing their growth and multiplication. This action disrupts the metabolism and energy production of the parasitic worms, leading to their immobilization and eventual death. Additionally, Albendazole interferes with an important system within the parasites known as the fumarate reductase system. This further contributes to its activity against these harmful organisms.
Certified content
Written By
MD Ayurveda
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
Albendazole can be taken orally (tablets and suspensions).
Age and Dose Restrictions
Albendazole is primarily meant for adults. It could also be given to children depending on the type of infection and dose adjustment is considered.
Contraindications
Albendazole is contraindicated in patients who have previously shown hypersensitivity to the medicine or any other benzimidazole derivatives.
It is also not recommended for use in patients with significant liver disease or abnormalities.
Other Medications to Avoid
Albendazole may interact with anticonvulsants (like phenytoin and carbamazepine), corticosteroids (like dexamethasone), anthelmintics (like praziquantel) and H2 blockers (such as cimetidine).
Overdose and Missed Dose
Overdosing on Albendazole might lead to possible adverse effects like abdominal pain, diarrhoea, headache, dizziness, and rash. If you suspect an overdose, it is advised to consult your doctor immediately.
If a dose is missed, it should be taken as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids may help manage some gastrointestinal side effects like abdominal pain and nausea.
Resting and avoiding sudden movements can help manage dizziness or vertigo.
Use in Driving and Operating Machinery
Albendazole may cause dizziness in some patients; if you experience this side effect, it is advised to avoid driving and any activity that requires high levels of alertness or physical coordination.
Use in Pregnancy and Lactation
Albendazole is not recommended for use during pregnancy unless absolutely necessary, due to potential risks to the foetus and breastfeeding mothers should avoid Albendazole, as it can pass into breast milk and potentially harm the nursing infant.
Caution in Other Conditions
Patients with liver disease, bone marrow suppression, or a history of these conditions should exercise caution when using Albendazole.
Regular monitoring of liver function tests and blood counts is advised in these patients.
Special Dietary and Lifestyle Recommendations
Regular handwashing, especially before meals, can help prevent some types of worm infections that Albendazole is used to manage.
Keeping your living environment clean and disinfected could also help prevent the spread of parasites.
Frequently asked questions
How long does Albendazole stay in the body?
The metabolite of Albendazole achieves peak plasma concentrations 2–5 hours after taking it orally and has a half-life of 8–12 hours in the body.
Are there any natural alternatives to Albendazole?
While there might be natural remedies that claim to manage parasitic worm infections, none are clinically proven to be as effective as Albendazole. Always consult a doctor before starting any new medication regimen.
Does Albendazole have any impact on fertility?
Albendazole is not known to affect fertility. However, it should be avoided during pregnancy due to the potential risk of teratogenicity.
Can Albendazole be used for all types of worm infections?
Albendazole is effective against various forms of parasitic worm infections. However, it is important to take it only when prescribed by a doctor.
Can Albendazole be taken on a daily basis?
The dosage of Albendazole varies depending on the type of infection and the patient's age and weight. It should be taken as directed by your doctor.
How long does it take for Albendazole to start working?
The exact time for Albendazole to start showing effects can vary from person to person and also depends on the type of parasitic infection being managed.
Is there a preferred time to take Albendazole?
Albendazole should ideally be taken with meals as it enhances its absorption and bioavailability. The exact time can be suggested by your doctor.
Albendazole in other salts
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