Adenosine
Uses of Adenosine
The primary use of Adenosine is in managing paroxysmal supraventricular tachycardia (PSVT), an abnormally fast heart rhythm disorder. It belongs to the group of anti-arrhythmic medications.
Additionally, it also finds use during cardiac stress testing, where it helps diagnose coronary artery disease by dilating the coronary arteries and increasing the blood flow to the heart.
Side effects of Adenosine
Flushing
Chest discomfort
Shortness of breath (dyspnea)
Headache
Dizziness
How Adenosine works
Adenosine is a purine nucleoside that naturally occurs in all human cells.
It works by slowing down the electrical impulses that control heart rhythm, allowing the heart to return to a normal rate. Adenosine attaches itself to adenosine A1 receptors on the surface of heart muscle cells, inhibiting the activity of the AV node. This group of cells conducts electrical impulses from the atria to the ventricles.
Certified content
Written By
MD Ayurveda
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Adenosine is available in (injection).
Age and Dose Restrictions
This medicine is meant for adults and children.
Contraindications
Adenosine is contraindicated in patients with second or third-degree heart block, sick sinus syndrome, long QT syndrome, or severe hypotension. It should be used cautiously in patients with asthma or COPD.
Other Medications to Avoid
This medicine may interact with antiplatelet medications (dipyridamole), methylxanthines (like caffeine and theophylline), and anti-convulsants (carbamazepine).
Overdose and Missed Dose
An overdose of Adenosine may lead to symptoms such as flushing, chest discomfort, shortness of breath, headache, dizziness, nausea, bronchospasm, atrial fibrillation, ventricular arrhythmias, heart block, seizures or allergic reactions. If you observe any of these symptoms, inform your doctor immediately.
In case you miss a dose of this medicine, consult your doctor for guidance.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage side effects like flushing and dizziness.
Resting or sitting down can help manage feelings of lightheadedness.
You may feel better if you take the medication at a certain time of day. Experiment with different times to see what works best for you.
Use in Driving and Operating Machinery
Adenosine may cause dizziness or lightheadedness, which could affect your ability to drive or operate machinery.
Avoid driving or operating heavy machinery if you feel these side effects.
Use in Pregnancy and Lactation
It is unknown whether Adenosine can cause harm to the fetus during pregnancy or if it is excreted in breast milk.
Consult your doctor before using this medicine during pregnancy and lactation.
Caution in Other Conditions
Adenosine should be used cautiously in patients with asthma, COPD, heart problems, or seizures.
Special Dietary and Lifestyle Recommendations
Patients taking Adenosine should avoid consumption of caffeine and other methylxanthine-containing foods and beverages for at least 12 hours before a cardiac stress test.
Regular monitoring of heart rate and rhythm is recommended for those on Adenosine.
Regular checkups with your doctor are advised to monitor the effectiveness of the medication.
Frequently asked questions
Is Adenosine a naturally occurring substance?
Yes, Adenosine is a naturally occurring substance found in every cell of our body. It is a purine nucleoside composed of an adenine molecule attached to a ribose sugar molecule.
What is the main use of Adenosine?
Adenosine is majorly used to manage certain heart rhythm disorders, particularly paroxysmal supraventricular tachycardia (PSVT).
How long does the effect of Adenosine last?
The effect of Adenosine usually lasts for only a few minutes because it is rapidly cleared from the circulation.
Will taking Adenosine affect my mood or emotions?
There is currently no evidence to suggest that Adenosine affects mood or emotions. However, different individuals may respond differently to any medication.
Does Adenosine need to be administered by a healthcare provider?
Yes, Adenosine is usually administered intravenously by a healthcare provider due to its short half-life and rapid action.
Can Adenosine cause allergic reactions?
Though rare, Adenosine has been known to cause allergic reactions in some patients.
Is Adenosine available as a brand-name medicine and as a generic medicine?
Yes, Adenosine can be availed both as a generic medicine and under the brand name Adenocard.
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